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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIPA1L1
All Species:
22.73
Human Site:
S267
Identified Species:
62.5
UniProt:
O43166
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43166
NP_056371.1
1804
200029
S267
D
V
I
D
G
P
I
S
Q
R
E
N
L
R
L
Chimpanzee
Pan troglodytes
XP_510040
1804
199959
S267
D
V
I
D
G
P
I
S
Q
R
E
N
L
R
L
Rhesus Macaque
Macaca mulatta
XP_001084201
1804
200030
S267
D
V
I
D
G
P
I
S
Q
R
E
N
L
R
L
Dog
Lupus familis
XP_537502
1806
199834
S267
D
V
L
D
G
P
I
S
Q
R
E
N
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0T5
1782
197013
S267
D
V
I
D
G
P
I
S
Q
R
E
N
L
R
L
Rat
Rattus norvegicus
O35412
1822
201906
S267
D
V
I
D
G
P
I
S
Q
R
E
N
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMV8
730
80773
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PF44
1015
114125
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785253
1625
180489
D185
R
R
H
N
T
S
P
D
G
K
Y
F
E
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
96.9
N.A.
94.6
93.3
N.A.
N.A.
20.2
N.A.
21.1
N.A.
N.A.
N.A.
N.A.
32.6
Protein Similarity:
100
99.9
99.7
98.5
N.A.
97
95.7
N.A.
N.A.
28.6
N.A.
33.4
N.A.
N.A.
N.A.
N.A.
49.5
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
67
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
67
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
67
0
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
56
0
0
0
67
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
0
0
0
0
0
67
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
67
0
0
0
% N
% Pro:
0
0
0
0
0
67
12
0
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% Q
% Arg:
12
12
0
0
0
0
0
0
0
67
0
0
0
67
0
% R
% Ser:
0
0
0
0
0
12
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _